Corrigendum to “Protosappanin A protects against experimental autoimmune myocarditis, and induces metabolically reprogrammed tolerogenic DCs” (Pharmacol. Res. 146 (2019) 104269)
نویسندگان
چکیده
منابع مشابه
Mononuclear cell secretome protects from experimental autoimmune myocarditis
AIMS Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients. Experimental autoimmune myocarditis (EAM) is a CD4+ T cell-dependent model, wh...
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Captopril, an angiotensin-converting enzyme inhibitor, is widely used in the treatment of a variety of cardiomyopathies, but its effect on autoimmune myocarditis has not been addressed experimentally. We investigated the effect of captopril on myosin-induced experimental autoimmune myocarditis. A/J mice, immunized with syngeneic cardiac myosin, were given 75 mg/L of captopril in their drinking ...
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BACKGROUND Myosin-induced autoimmune myocarditis of rats is a model of human dilated cardiomyopathy. Resveratrol is a natural polyphenol found in grapes and wine that is reported to have cardioprotective and immunomodulatory effects. METHODS AND RESULTS To examine the effect of resveratrol on myocarditis, vehicle or resveratrol (50 mg/kg per day) was administered to cardiac myosin immunized r...
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225 Received May 7, 2012; revision accepted for publication June 21, 2012. doi: 10.1620/tjem.227.225 Correspondence: Jian Hu, Department of Cardiology, The First Hospital of China Medical University, China Medical University, Heping District, 155 North Nanjing Street, Shenyang 110001, P.R. China. e-mail: [email protected] Emodin, a Naturally Occurring Anthraquinone, Ameliorates Experimental...
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In this study, we tested the hypothesis that MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one; edaravone), a novel free radical scavenger, protects against acute experimental autoimmune myocarditis (EAM) in rats by the radical scavenging action associated with the suppression of cytotoxic myocardial injury. Recent evidence suggests that oxidative stress may play a role in myocarditis. We administer...
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ژورنال
عنوان ژورنال: Pharmacological Research
سال: 2020
ISSN: 1043-6618
DOI: 10.1016/j.phrs.2020.105177